| Name |
System |
Subsystem |
Players |
Genre |
Release Date |
| EA Playground | Nintendo DS | | | Party/Parlor | Oct 22, 2007 |
| Earthworm Jim | Nintendo DS | DSiWare | 1 | Action | May 10, 2010 |
| Easter Eggztravaganza | Nintendo DS | DSiWare | 1 | | Feb 28, 2013 |
| Eco-Creatures: Save the Forest | Nintendo DS | | 1 - 4 | Strategy | Mar 4, 2008 |
| Ed, Edd n Eddy: Scam of the Century | Nintendo DS | | | Adventure | Oct 23, 2007 |
| Egg Monster Heroes | Nintendo DS | | 1 - 4 | Strategy | TBA |
| EJ Puzzles: Hooked | Nintendo DS | DSiWare | 1 | Puzzle | Jan 10, 2011 |
| Elebits: The Adventures of Kai and Zero | Nintendo DS | | 1 - 4 | Puzzle | Jan 6, 2009 |
| Electroplankton | Nintendo DS | | 1 | | Jan 9, 2006 |
| Electroplankton Beatnes | Nintendo DS | DSiWare | 1 | | Nov 9, 2009 |
| Electroplankton Hanenbow | Nintendo DS | DSiWare | 1 | | Nov 9, 2009 |
| Electroplankton Nanocarp | Nintendo DS | DSiWare | 1 | | Nov 9, 2009 |
| Electroplankton Rec-Rec | Nintendo DS | DSiWare | 1 | | Nov 9, 2009 |
| Eledees: The Adventure of Kai and Zero | Nintendo DS | | | RPG | TBA |
| Elemental Masters | Nintendo DS | DSiWare | 1 - 2 | | Mar 8, 2010 |
| Elf Bowling Collector's Edition | Nintendo DS | | | | Nov 2007 |
| Elite Beat Agents | Nintendo DS | | 1 - 4 | Rhythm | Nov 8, 2006 |
| Elite Forces: Unit 77 | Nintendo DS | | | Action | Apr 28, 2009 |
| El Tigre: The Adventures of Manny Rivera | Nintendo DS | | | | Oct 29, 2007 |
| Emergency! Disaster Rescue Squad | Nintendo DS | | | | Mar 24, 2009 |
| Emergency Room: Real Life Rescues | Nintendo DS | | | Simulation | Jun 16, 2009 |
| Enchanted | Nintendo DS | | | Adventure | Nov 13, 2007 |
| Ener-G Dance Squad | Nintendo DS | | | Sports | Oct 2008 |
| Ener-G Gym Rockets | Nintendo DS | | | Sports | Oct 2008 |
| English Training 2 (tentative title) | Nintendo DS | | | Simulation | Oct 2007 |
| English Training: Have Fun Improving Your Skills | Nintendo DS | | | Simulation | Oct 13, 2006 |
| Equestrian Training Stages 1 to 4 | Nintendo DS | | | Simulation | Nov 7, 2008 |
| Eragon | Nintendo DS | | | RPG | Q4 2006 |
| Escape the Virus: Shoot'em Up | Nintendo DS | DSiWare | 1 | Puzzle | Aug 30, 2012 |
| Escape the Virus: Swarm Survival | Nintendo DS | DSiWare | 1 | Strategy | Jun 28, 2012 |
| Escape Trick: Convenience Store | Nintendo DS | DSiWare | 1 | Adventure | Nov 17, 2011 |
| Escape Trick -Ninja Castle- | Nintendo DS | DSiWare | 1 | Puzzle | Sep 22, 2011 |
| Eternal Chronicle | Nintendo DS | | | RPG | TBA |
| Etrian Odyssey | Nintendo DS | | 1 | RPG | May 15, 2007 |
| Etrian Odyssey II: Heroes of Lagaard | Nintendo DS | | 1 | RPG | Jun 17, 2008 |
| Etrian Odyssey III: The Drowned City | Nintendo DS | | | RPG | Sep 21, 2010 |
| Exit DS | Nintendo DS | | | Puzzle | Nov 4, 2008 |
| Extreme Hangman | Nintendo DS | DSiWare | 1 - 2 | Puzzle | Feb 8, 2010 |
| Extreme Hangman 2 | Nintendo DS | DSiWare | | Puzzle | Jul 14, 2011 |
| Eyeshield 21: MAX DEVILPOWER! | Nintendo DS | | 1 - 2 | Sports | Feb 2, 2006 |
