Aside from taking different forks in the sky.
You'll be able to make Star Fox Zero as easy - or as hard - as you want.
In an interview with Time Magazine, Shigeru Miyamoto confirmed that the April 22 release will feature plenty of options for adjusting the game's difficulty. Among the options will be a challenge mode for experienced players where the Arwing takes/deals more damage, as well as a "invincibility" option for newcomers.
It isn't clear as to whether the option refers to something similar to the Super Guide or an easily obtainable in game powerup.