Nintendo remain confident about their manufacture and launch estimates.
Nintendo's global president, Satoru Iwata, is confident that there will be no significant manufacturing issues that will affect their business, and they are confident in their estimates for the launch timeline.
He gave the example of a boom in smartphones affecting LCD production as something that was not a worry. LCD supply was said to have caused shortages during the early days of the Nintendo DS Lite. They were ready to show the Wii U at E3 this year as based on their estimates, it will be ready for launch in 2012.
On another note regarding manufacture, the strength of the yen has meant that Nintendo are shifting to paying for goods manufacturing costs in U.S. dollars to mitigate the impact. An appreciating yen means that the U.S. market becomes less profitable, and they are taking measures to make payments in U.S. dollars as much as possible to remain competitive in the largest market for games in the world.